SELKO AOmix

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Supporting beef cattle performance by improving oxidative status with highly bioavailable antioxidants from Selko AOmix

Figure 1. Selko AOmix contains antioxidants that function throughout the cell

Figure 2. In-vitro assessment of antioxidative equivalence of Selko AOmix vs. synthetic vitamin E-50 using the KRL method (kit radicaux libres), showing that Selko AOmix is 5 times more potent.

The role of Selko AOmix in mitigating oxidative stress

Beef cattle suffering from oxidative stress can have various problems, including reduced average daily gain and immune function. Beef in cow-calf operations can suffer from poor reproductive performance as a result of oxidative stress. Oxidative stress in beef cattle can be mittigated with a balanced diet containing adequate levels of antioxidants. Factors such as their bioavailability and solubility can impact effectiveness of antioxidants. To address concerns about bioavailability of antioxidants in beef cattle, specially formulated alternatives to vitamin E, such as Selko AOmix, have been developed for cattle. These alternatives provide optimal digestibility and cover the complete water-to-fat-soluble range. This ensures antioxidants are delivereds to every part of the beef cattle's cells.

Crucial factors in antioxidant effectiveness in beef cattle

  • If the antioxidant in the supplement for beef cattle is not well-digested, fewer antioxidants become available for absorbtion by the animal. Absorption and the distribution into the cells are important factors influencing bioavailability of antioxidants in beef cattle.
  • Another factor that impacts effectiveness of an antioxidant for beef cattle is its water vs. fat solubility, which can vary widely between antioxidant products for ruminants. Solubility of antioxidants for beef cattle determines where they are distributed in the body. Vitamin E for instance mainly delivers its antioxidant effect at the cell membrane, and has less impact on the external or internal environment of the cell (see Figure 1).

Ruminants have different digestive systems compared to monogastrics. As a result, antioxidants in their feed differ in bioavailability. Bioavailability of antioxidants in ruminants is directly linked to the polyphenol’s susceptibility to rumen fermentation, the type of fermentation products produced, and the bioavailability of bypass polyphenols of polyphenol fermentation products in beef cattle. For this reason, Selko has formulated ruminant specific alternatives to partially replace vitamin E for beef cattle. Plant extracts that are included in Selko AOmix for beef cattle either contain bypass polyphenols or polyphenols which are fermented into potent and bioavailable metabolites. Selko AOmix is therefore capable of substituting and/or complementing the antioxidant protection that most cattle currently get from Vitamin E supplementation above requirements (see Figure 2).

Selko AOmix is a cost-effective solution to partially replace vitamin E for beef cattle

Administration

The natural polyphenols in Selko AOmix are either water-soluble, biphasic (soluble in both water and fat) or fat-soluble, ensuring antioxidant support throughout the cellular environment.

Selko AOmix can partially replace more expensive antioxidant ingredients in a feed formulation, such as vitamin E supplemented above beef cattle requirements. Due to the optimal bioavailability and distribution characteristics, polyphenols can support growth, fertility, and offspring antioxidant status. Adding Selko AO Mix to a feed formulation also improves stability of other vitamins.

The advised Vitamin E Level in combination with feeding Selko AO Mix:

Current Vitamin E Vitamin E New AO Mix R
Receiving cattle IU/day 225 100 125
Finishing cattle IU/day 500 240 360
Growing cattle IU/kg DMI 20 15 5

Connect with our experts

Navigating the daily operations of dairy and beef farming is challenging, and the transition towards sustainable practices raises numerous questions.

Selko ruminant specialists are dedicated to help you assess and address these challenges effectively. For personalized support and expert advice on achieving sustainable and profitable farming, get in touch with our team today.

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Figure 1. Selko AOmix contains antioxidants that function throughout the cell

Figure 2. In-vitro assessment of antioxidative equivalence of Selko AOmix vs. synthetic vitamin E-50 using the KRL method (kit radicaux libres), showing that Selko AOmix is 5 times more potent.

Features

The natural antioxidants in Selko AOmix for beef have been selected for ideal digestibility and cover the complete water-to-fat-soluble range, ensuring optimal delivery of antioxidant activity in every part of the cell.

Benefits

Damaging effects of free radicals are mitigated by the antioxidants in Selko AOmix. Feeding Selko AOmix to beef cattle can improve performance under challenging conditions such as transition into the feedlot or periods of heat stress. Selko AOmix can reduce costs of a feed formulation for beef cattle by replacing more expensive vitamin E in case levels that are fed exceed NASEM recommendations for vitamin E levels fed to beef cattle for antioxidant purposes.

Selko® | sharing latest scientific insights

Free techbook with expert insights

Don’t miss this opportunity to gain expert knowledge on optimizing ruminant production. This essential resource, featuring the latest scientific insights on trace minerals, is available for digital download or as a limited-edition paperback for early registrants. Tick the box in the form if you prefer the paperback version.

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We've just sent you an email to confirm your request and provide further details.If you've requested the paperback edition, please check your email, as we'll need additional shipping information from you. We appreciate your interest and look forward to helping you enhance your beef farming operations with the latest insights on trace minerals.

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You can access all of our documentation about the science behind Selko products and services as well as Selko technical bulletins about ruminant challenges and technical product data sheets.

Picture of Selko AOmix brochure

Polyphenols: a cost-effective solution to partially replace vitamin E

Oxidative stress in beef cattle occurs as a result of normal metabolism and can be a hidden threat. It can have a nnegative impact on your cattle's well-being. Download our product brochure to find out how you can protect your beef cattle herd from oxidative stress, can occur following entry into feedlots, as a result of heat stress, feeding high-concentrate diets, or health issues that are common in feedlot cattle. Improve beef cattle health with Selko's proven solutions.

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